Host-derived macromolecules present in saliva, such as salivary mucins, are ________.

Host-derived macromolecules present in saliva, such as salivary mucins, are ________.

• A. Glycosylated proteins
• B. Non-glycosylated proteins
• C. Lipids
• D. Nucleic acids

Answer: (A)

Glycosylated proteins. Host-derived macromolecules in saliva, such as salivary mucins, are proteins that carry extensive carbohydrate attachments. Those sugar chains (glycans) give mucins their large size, negative charge, and ability to retain water, creating the lubricating, gel-like quality of saliva. The glycosylation also shapes how oral microbes interact with mucins, providing binding motifs and influencing adhesion. They are not lipids or nucleic acids, and they are not non-glycosylated proteins, which is why glycosylated proteins is the best description.

Glycosylated proteins. Host-derived macromolecules in saliva, such as salivary mucins, are proteins that carry extensive carbohydrate attachments. Those sugar chains (glycans) give mucins their large size, negative charge, and ability to retain water, creating the lubricating, gel-like quality of saliva. The glycosylation also shapes how oral microbes interact with mucins, providing binding motifs and influencing adhesion. They are not lipids or nucleic acids, and they are not non-glycosylated proteins, which is why glycosylated proteins is the best description.